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Tianeptine sodium salt

CAS No.: 30123-17-2
Product introduction:Tianeptine sodium salt is an atypical tricyclic antidepressant developed and marketed by Servier Laboratories. Unlike conventional selective serotonin reuptake inhibitors (SSRIs), tianeptine acts as a selective serotonin reuptake enhancer (SSRE), increasing serotonin reuptake in the brain. The sodium salt form provides improved water solubility and stability for pharmaceutical formulation. It has been used clinically since the late 1980s in Europe, Asia, and Latin America for the treatment of major depressive disorder. Tianeptine exhibits a unique pharmacological profile that distinguishes it from all other antidepressant classes.

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CAS No.:30123-17-2

Tianeptine sodium salt is a white to off-white crystalline powder. Its molecular formula is C21H24ClN2NaO4S with a molecular weight of approximately 458.93 g/mol. The compound is freely soluble in water and soluble in various organic solvents. It is the sodium salt of tianeptine acid, resulting from the reaction of tianeptine with sodium hydroxide, forming a stable salt with improved aqueous solubility compared to the free acid form. The compound should be stored in a dry, cool environment, protected from light, to maintain its stability and potency.

Core Functions:

  • Active pharmaceutical ingredient (API) in antidepressant drug products for major depressive disorder

  • Treatment of asthma and irritable bowel syndrome (in some countries as adjunctive therapy)

  • Research use in neuropharmacology studies of serotonin reuptake enhancement mechanisms

  • Investigation of neuroplasticity and stress-induced brain changes

  • Reference standard for analytical method development and quality control

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